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Wednesday, August 18, 2010

Show Me The Data, Part 2

I wanted to reaffirm my position on Italian Dr. Paulo Zamboni's "Liberation Treatment" hypotheses that have created something of a controversy in the Multiple Sclerosis /Canadian Politics game...although I respect Dr. Zamboni's professional credentials, I'm fairly certain that those hypotheses cannot be safely or adequately tested on this exceedingly-rare disease without potentially disastrous results...primarily to the public-perception of the validity and value of otherwise well-respected and well-tested research into M.S.

I think the most ominous (mis-)connection would be the mis-perceived notion that MULTIPLE SCLEROSIS (an affliction that damages neural-myelin) is anything like ARTERIOSCLEROSIS (clogging of arteries with ill-digested matter).

The vague-connection is found in the ambiguous root -sclerosis- which suggests many inaccurate ideas...at least to the untrained mind.

Again, I'm not trying to debunk Dr. Zamboni...just reminding novice readers that THEORY is the end-result of intensive scientific-testing of any HYPOTHESIS...and given the rarity of M.S. (even though it may seem like a lot of people in any given country have M.S.), there are only estimated to be 2-3 million people in this whole world of 6.9 billion people who appear to have M.S....that makes for some real obstacles in proving ANY HYPOTHESIS about M.S. true.

--mattergy

Addendum August 19, 2010
I just wanted to clarify a few things about "Liberation Treatment". First of all, Dr. Zamboni is proposing a heretofore unexplored or (ill-explored) connection between Vascular flow in neural-tissues and M.S. His Hypotheses are focused on blood-flow deficiencies that result in an overabundance of Iron in neural-tissues resulting in dysfunction. This is a novel revelation, if true...but the idea that surplus Iron in neural-tissue is what causes M.S. to appear is unproven.


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